Colonic and small intestinal response to intravenous prostaglandin F 2 a and E 2 in man
نویسندگان
چکیده
were measured in eight healthy males by simultaneous ileal and colonic perfusion. Ileal flow was increased by PGF2e (six subjects)from a mean of 169 ml min-1 to 4 63 ml min-1 (p < 0.01); it also increased in the two subjects given PGE2. Colonic absorptive function was not significantly diminished by either prostaglandin. These results suggest that diarrhoea due to prostaglandins originates in the small intestine.
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